TRANSCRIPTOME ANALYSIS OF THE ENDANGERED NOTOPTERYGIUM INCISUM: COLD-TOLERANCE GENE DISCOVERY AND IDENTIFICATION OF EST-SSR AND SNP MARKERS

Transcriptome analysis of the endangered Notopterygium incisum: Cold-tolerance gene discovery and identification of EST-SSR and SNP markers

Notopterygium incisum C.C.Ting ex Vacuum Cleaners H.T.Chang (Apiaceae) is an endangered perennial herb in China.The lack of transcriptomic and genomic resources for N.incisum greatly hinders studies of its population genetics and conservation.In this study, we employed RNA-seq technology to characterize transcriptomes for the flowers, leaves, and s

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Poxvirus Interactions with the Host Ubiquitin System

The ubiquitin system has emerged as a master regulator of many, if not all, cellular functions.With its large repertoire of conjugating and CHO-LES-TERIN ligating enzymes, the ubiquitin system holds a unique mechanism to provide selectivity and specificity in manipulating protein function.As intracellular parasites viruses have evolved to modulate

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DISC-3D: dual-hydrogel system enhances optical imaging and enables correlative mass spectrometry imaging of invading multicellular tumor spheroids

Abstract Multicellular tumor spheroids embedded in collagen I matrices are common in vitro systems for the study of solid tumors that reflect the physiological environment and complexities of the in vivo environment.While collagen I environments are physiologically relevant and permissive of cell invasion, studying spheroids in such hydrogels prese

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